A NATURAL FOUNDATION FOR HEALING
Placentally-derived human amniotic membrane (AM) is a potent source of pro-healing growth factors and anti-inflammatory cytokines and has successfully been used in regenerative medicine for over a century. Early users of AM for wounds and post-surgical applications noted how the membrane seemed to disappear and integrate with the patient’s own tissue without a host reaction. This apparent immune neutrality is a result of mechanisms that suppress and modulate the immune system.
The use of AM was initially limited due to storage challenges associated with use of the fresh tissue. Modern processing methods – including dehydration – have delivered options that have longer shelf lives, can be stored at ambient temperatures, and can be terminally sterilized. These advances also allow manufacturers to create thinner coverings that are suitable for delicate ophthalmic use.
Today, dehydrated human amniotic membrane (DHAM) continues to be widely used and studied as an ophthalmic covering across a range of topical applications.